53 results
Elagolix (Orilissa) - Pharmacology Review
Elagolix is a small-molecule GnRH antagonist recently approved by the FDA for
Review Elagolix ... is a small-molecule ... the FDA for the treatment ... #Orilissa #Review ... #Overview
Suggested algorithm for treating irritable bowel syndrome-diarrheal type (IBS-D) 

#IBSD #diarrhea #Algorithm #irritable #bowel #syndrome #management
type (IBS-D) ... #IBSD #diarrhea ... irritable #bowel #syndrome ... #management #treatment ... #gastroenterology
Antifungal Azoles - Antibiotics Class Overview

Mechanism:  inhibit ergosterol synthesis (important component of fungal cell membranes)
Antifungal Azoles - Antibiotics ... Class Overview ... Isavuconazole(PO or IV) #Pharmacology ... #Antibiotics #Review ... #Overview #Azoles
Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview

Mechanism: binds ergosterol in membrane and
Abelcet, Ambisome - Antibiotics ... Class Overview ... (voriconazole is ... #Pharmacology #Antibiotics ... #Review #Overview
Irritable Bowel Syndrome (IBS) Treatment Algorithm

IBS-Constipation:
 • Constipation: Osmotic laxatives
 • Abdominal pain: Antispasmodics

IBS-Diarrhea:
 • Diarrhea:
Irritable Bowel Syndrome ... (IBS) Treatment ... #IBS #Treatment ... #Management #Algorithm ... #gastroenterology
Synercid (Quinupristin/Dalfopristin) (IV) - Antibiotics Class Overview

Mechanism: “Streptogramins”– inhibits sequential steps in ribosomal synthesis
Spectrum: covers MRSA
Dalfopristin) (IV) - Antibiotics ... Class Overview ... Not much, as it is ... #Pharmacology #Antibiotics ... #Review #Overview
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... Class Overview ... when Pseudomonas is ... #Pharmacology #Antibiotics ... #Review #Overview
IBS-C Pharmacotherapy

Polyethylene glycol
Lubiprostone
Linaclotide
Plecanatide
Tegaserod
Tenapanor

#IBSC #IBS #Constipation #Irritable #Bowel #Syndrome #pharmacology #table #comparison #management #treatment
IBS-C Pharmacotherapy ... Irritable #Bowel #Syndrome ... #pharmacology # ... table #comparison #management ... #treatment
IBS-D Pharmacotherapy

Loperamide
Rifaximin
Eluxadoline
Alosetron
Antispasmodics
Tricyclic antidepressants
SSRIs

#IBSD #IBS #Diarrhea #Irritable #Bowel #Syndrome #pharmacology #table #comparison #management #treatment
IBS-D Pharmacotherapy ... Irritable #Bowel #Syndrome ... #pharmacology # ... table #comparison #management ... #treatment
Flutycosine - Antibiotics Class Overview
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Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
Flutycosine - Antibiotics ... Class Overview ... B for initial management ... #Pharmacology #Antibiotics ... #Review #Overview