11 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... APML, CLL Acute ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... leukemia Management ... Myelodysplastic #Syndrome ... #MDS #Diagnosis ... #Management #treatment
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
(transfusions, antibiotics ... Can progress to MDS ... or acute leukemia ... #diagnosis #management ... #treatment #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
- Summary Cancer ... • Neutropenia, anemia ... • Richter’s Syndrome ... ’s lymphoma or acute ... syndrome • Smoldering
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... marrow-failure syndromes ... myelodysplastic syndrome ... #diagnosis #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myelodysplastic syndromes ... Cell Leukemia ... isoniazid) • Antibiotics ... #diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
hemolysis, deficiency anemia ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... Acute febrile ... dermatosis (Sweets Syndrome ... - Lupus - Leukemia ... #diagnosis #dermatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
dermatomyositis, Sjogren syndrome ... lymphoma • Evans' syndrome ... lymphoproliferative syndrome ... Shrinking lung syndrome ... Hodgkin lymphoma and leukemia
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
leukemia • Solitary ... changes (POEMS syndrome ... ovarian tumors, lung cancers ... anemia • Other ... #differential #diagnosis