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aplastic chronic lymphocytic mds algorithm apml cancer causes differential differentiation hemeonc hemophagocytic hlh lymphohistiocytosis myelodysplasia secondary sweet workup
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - ... Diagnosis and Management ... leukemia Management ... #Syndrome #MDS ... #treatment #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
): • Acute infection ... malignancies • Anemia ... syndrome • Myelofibrosis ... Chronic myeloid leukemia ... #Causes #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... APML, CLL Acute ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Syndromes (MDS) ... Cell Leukemia ... isoniazid) • Antibiotics ... #Syndromes #diagnosis ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... • Richter’s Syndrome ... ’s lymphoma or acute ... syndrome • Smoldering ... #oncology #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
(transfusions, antibiotics ... progress to MDS or acute ... leukemia • Associated ... #diagnosis #management ... #treatment #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... syndrome (MDS) ... #oncology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Overview: • Most ... 5) Symptoms of anemia ... #oncology #hematology ... #hemeonc #diagnosis ... #management
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... Acute febrile ... dermatosis (Sweets Syndrome ... #diagnosis #dermatology ... #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Induce blast cell ... Differentiation #Syndrome ... #management #hematology ... #oncology
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