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management differential anemia intravascular rheumatology syndrome adjusted age aplastic arterial cascade centralretinalartery crao ddimer dermatology dic dimer disseminated embolism extravascular
Learning about thromboelastography (TEG). - Tom Fadial @thame #Diagnosis #Hematology #Coagulation #Pharmacology #Thromboelastogram #TEG #Interpretation #Thromboelastography #Laboratory
Fadial @thame #Diagnosis ... #Hematology #Coagulation ... #Pharmacology # ... Thromboelastography #Laboratory
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
(DIC) Overview ... protein C and S Pathophysiology ... venipuncture sites Laboratory ... #diagnosis #causes ... treatment #management #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... intravascular coagulation ... Drugs (Beta lactam antibiotics ... #hematology #anemia
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... intravascular coagulation ... and other causes ... Venous #Arterial #pathophysiology ... #hematology #differential
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
) -> Increased coagulation ... • Hematologic ... retinal edema caused ... Occlusion #CRAO #pathophysiology ... ophthalmology #diagnosis
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
• A clinical diagnosis ... Rule out other causes ... other etiology • Laboratory ... syndrome with acne: antibiotics ... #Dermatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia - Overview ... and petechiae Causes ... - β-lactam antibiotics ... Anemia #oncology #hematology ... #diagnosis #management
D-dimer Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
indicate that coagulation ... age, which can cause ... Ddimer #dimer #pathophysiology ... #hematology #differential ... #diagnosis #age
Review of the Coagulation Cascade Traditional Model: • Parallel extrinsic and intrinsic pathways. Contemporary Model: • 4 key
Review of the Coagulation ... Initiation phase caused ... #Cascade #diagnosis ... #models #hematology ... #pathophysiology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome Overview ... Sjogren's Syndrome Diagnosis ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... lubricants • Pharmacologic
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