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differential chronic cll diffuse focal generalized localized lymphocytic mds myelodysplastic pruritus secondary systemic aplastic classification common cvid extravascular gap globulin
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
, Lymphoma, Metastatic ... #LAD #Differential ... #Diagnosis #Algorithm ... #Causes #Hematology ... #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... #LAD #Differential ... #Diagnosis #Algorithm ... #Causes #Hematology ... #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Lymphadenopathy ... #LAD #Differential ... #Diagnosis #Algorithm ... #Causes #Hematology ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... activity • ↓ LAP ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute leukemia ... #hematology #oncology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Leukemia, Tumour ... Non-lmmune: • HELLP Syndrome ... #Algorithm #Causes ... #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... • Richter’s Syndrome ... • Sezary syndrome ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
CLL) - Summary Overview ... 5) Symptoms of anemia ... to large cell lymphoma ... #oncology #hematology ... #management
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential: • Lymphoma ... • Leukemia ... Myelodisplastic syndrome ... #generalized #dermatology ... #Algorithm #causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... ) - HELLP syndrome ... e.g. lupus, CLL, lymphoma ... #hematology #anemia
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