12 results
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... telomeropathy Cancer ... Differential #Diagnosis #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Differential Diagnosis Algorithm ... HLH syndrome 5. ... Acquired Aplastic Anemia ... marrow failure syndrome ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Differential Diagnosis Algorithm ... HLH syndrome 5 ... Acquired Aplastic Anemia ... marrow failure syndrome ... #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
- Overview Who ... bone marrow + pancytopenia ... • Peripheral Pancytopenia ... Treatment: ... #oncology #hematology
Causes of Dyspnea - Differential Diagnosis Algorithm
Cardiac:
 • Dysrhythmia
 • Ischemia
 • Cardiomyopathy
 • Valvular disease
Causes of Dyspnea ... Differential Diagnosis Algorithm ... Superior vena cava syndrome ... Emphysema • Cancer ... • Anxiety • Anemia
Dyspnea - Considerations with Malignancy
Directly Malignancy Related:
 - Lymphangitic spread to lung
 - Malignant pleural effusion
Dyspnea - Considerations ... metastases Treatment ... - Cytopenias (anemia ... #algorithm #differential ... diagnosis #oncology #cancer
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Malignancy: Metastatic cancer ... Kawasaki, Nephrotic syndrome
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's Lymphoma Overview ... • Cough • Dyspnea ... Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Treatment
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... - infiltrates (anemia ... • Bone pain, dyspnea ... • Tumor lysis syndrome ... lymphoid organs When Cancer
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... • Neutropenia, anemia ... microglobulin Treatment ... • Richter’s Syndrome ... leukemia • Sezary syndrome