13 results
Antiplatelet Conversion - Switching Between P2Y12 Inhibitors
Oral P2Y12 inhibitors vary in potency and pharmacokinetic and dynamic
Clopidogrel to Prasugrel ... De-escalation in Potency: Prasugrel ... High Potency: Prasugrel ... Ticagrelor to Prasugrel ... #pharmacology #
Oral P2Y12 Inhibitor Pharmacology

 • Clopidogrel
 • Prasugrel
 • Ticagrelor

By Kyle Fischer, PharmD @Kfischer_10

#P2Y12 #Inhibitor #Pharmacology
Oral P2Y12 Inhibitor ... Pharmacology ... Clopidogrel • Prasugrel ... Kfischer_10 #P2Y12 ... #Inhibitor #Pharmacology
Trends in Platelet Adenosine Diphosphate P2Y12 Receptor Inhibitor Use and Adherence Among Antiplatelet-Naive Patients After Percutaneous
Adenosine Diphosphate P2Y12 ... Inhibitor Use and Adherence ... EBM #Cardiology #Adherence ... #Clopidogrel #Prasugrel
Antiplatelet Medications - Summary Table

Aspirin - Inhibits cyclooxygenase, preventing formation of thromboxane A2
 • Acute coronary
combination with P2Y12 ... anticoagulation in a-fib P2Y12 ... (clopidogrel, prasugrel ... - Inhibits the P2Y12 ... Summary #Table #Pharmacology
Antiplatelet Conversion - P2Y12 Inhibitor Switching
 • Clopidogrel (Plavix)
 • Prasugrel (Effient)
 • Ticagrelor (Brilinta)
Clopidogrel and
Antiplatelet Conversion - P2Y12 ... Clopidogrel and prasugrel ... active site of the P2Y12 ... Antiplatelet #Conversion #P2Y12 ... Inhibitor #Switching #pharmacology
Antiplatelet Conversion - Switching Between Oral P2Y12 Inhibitors
A, Switching between oral agents in the acute/early phase.
Switching Between Oral P2Y12 ... escalating to prasugrel ... ticagrelor to prasugrel ... CIRCULATIONAHA.117.031164 #P2Y12 ... #pharmacology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
1500ng/mL • Non-adherence ... check therapeutic adherence ... poor therapeutic adherence ... #rheumatology #pharmacology
Cangrelor - Pharmacology
Cangrelor (Kengreal) is a parenteral analogue of adenosine triphosphate
Cangrelor binds reversibly to the platelet
Cangrelor - Pharmacology ... to the platelet P2Y12 ... Antiplatelet: • Both prasugrel ... clopidogrel and prasugrel ... Cangrelor #Kengreal #Pharmacology
Clopidogrel (Plavix) and Clopidogrel Non-responders

Clopidogrel is an irreversible selective inhibitor of the platelet low-sensitivity adenosine diphosphate
diphosphate receptor: P2Y12 ... Nonresponders #pharmacology
Long-Acting Injectable (LAI) - Atypical Antipsychotics 
INVEGA TRINZA 3 MONTHS 
ARISTADA 2 MONTHS 
INVEGA 1 MONTH
SUSTENNA
Adherence to daily ... schizophrenia can make adherence ... Antipsychotics #Pharmacology