26 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Autoimmune • ITP • SLE ... Non-lmmune: • HELLP Syndrome ... HUS • DIC • Vasculitis ... • Infection ... #Hematology
Polyarteritis Nodosa (PAN) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines
 • Severe Disease → Remission
) - Vasculitis Management ... Algorithm - ACR ... immunosuppressive agent (e.g ... #Management #Treatment ... #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Hypersensitivity vasculitis ... Schönlein purpura • PAN ... Antiphospholipid-antibody syndrome ... • Vasculitis ... #differential #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Rebound effect from treatment ... Rheumatologic, Vasculitides ... Kawasaki, Nephrotic syndrome ... Matthew Ho, MD PhD ... #Algorithm #hematology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
disease (10%) : SLE ... (5%): PAN > GPA ... (3%) • Infections ... #semiology #signs ... #lesions #diagnosis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... Labs/Diagnosis: ... tissue disorder (e.g ... erythematosus (SLE ... Cryoglobulins #diagnosis
Mesenteric Ischemia - Differential Diagnostic Schema
Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA)
Acute
 - Venous
5% (PAN, [E]GPA ... inflammation (e.g ... Antiphospholipid syndrome ... hypovolemia), Meds/Treatments ... #algorithm
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Bacterial or viral infection ... Lyme disease, Vasculitis ... (e.g., PAN) ... #differential #diagnosis ... #rheumatology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
- Differential Diagnosis ... Algorithm Red ... papilledema • Horner syndrome ... lesion • CNS infection ... Matthew Ho, MD PhD
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
glucocorticoid treatment ... organ-specific signs ... or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia