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management differential oncology signs anemia arthritis hemolytic workup algorithm classification leukemia msk syndrome systemic treatment vasculitis agglutinin anemias aplastic apml
Pathophysiology, Signs and Symptoms of Hemolytic Anemia #Pathophysiology #Hemolytic #Anemia #hematology #diagnosis #signs #symptoms
Pathophysiology, ... Signs and Symptoms ... Hemolytic #Anemia #hematology ... #diagnosis #signs ... #symptoms
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential Diagnosis ... Algorithm Signs ... Hypersplenism, Infection ... Matthew Ho, MD PhD ... #Algorithm #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... , dyspnea, +/- CXR ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... organ-specific signs ... or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... • Recurrent infections ... Symptomatic anemia Diagnosis ... management #treatment #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
(Cold-induced symptoms ... Diagnosis: • hemolytic ... rewarming • Symptoms ... hemolytic #anemia #hematology ... #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... common • Imaging: CXR ... : >3 symptoms, or ... : Infection (sepsis ... #management #hematology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... and Symptoms: ... lung disease), PAH ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
blood donor • Pathophysiology ... ARDS to explain symptoms ... fluid balance, and CXR ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... counts may delay diagnosis ... #differential #diagnosis ... neutrophil #WBC #CBC #hematology ... #pathophysiology
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