93 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
- Differential ... Diagnosis Algorithm ... Signs of anemia ... Matthew Ho, MD PhD ... #hematology
De Winter's T Waves - Acute Sign of Proximal LAD Occlusion #Diagnosis #Cardiology #EKG #ECG #DeWinters
Waves - Acute Sign ... of Proximal LAD ... Occlusion #Diagnosis ... #Cardiology #EKG ... #ECG #DeWinters
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Extravascular #Causes #differential ... #diagnosis #hematology
Wellens' Sign: LAD-T Wave Inversion 
Life threatening T wave inversions in precordial leads. Often V2-V3 
Specific
Wellens' Sign: LAD-T ... Serial EKGS in pts ... #Wellens #Sign # ... EKG #ECG #Electrocardiogram ... #Diagnosis #Cardiology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Diagnosis Framework ... Macroangiopathic, Infections ... aciduria, Drugs (e.g ... Matthew Ho, MD PhD ... #Diagnosis #hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Diagnosis Algorithm ... • Thrombus (e.g ... Myeloproliferative disorders (eg ... Serum Sickness Hemolytic ... #Causes #Hematology
Colonic Thumbprint Sign on Abdominal XRay - Differential Diagnosis:
 • inflammatory bowel disease: UC and CD
Colonic Thumbprint Sign ... : UC and CD • infection ... (e.g. pseudomembranous ... #Differential # ... Diagnosis #radiology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
infiltration (e.g ... Marrow suppression (e.g ... Intrinsic RBC defects (e.g ... #anemia #differential ... #diagnosis #calculation
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
(Cold-induced symptoms ... Diagnosis: • hemolytic ... younger pts) Differential ... #anemia #hematology ... #diagnosis
Cardiac Amyloid - Diagnosis, Signs, Symptoms and Management

Clinical Presentation
- exertional dyspnea
- peripheral edema
- exertional syncope
- peripheral
Cardiac Amyloid - Diagnosis ... , Signs, Symptoms ... despite hx HTN) EKG ... Amyloidosis #Cardiac #Diagnosis ... #Symptoms #Cardiology