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Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Primary Biliary Cirrhosis ... pathophysiology #pbc #psc #hepatology ... #comparison
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
Antivirals #table #treatment ... #medications #infectiousdisease ... #hepatology #HepC
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
tolerant state - HBe-Ag ... indicated: • HBe-Ag ... Family history of cirrhosis ... or fibrosis • Cirrhosis ... Indications #management #hepatology
Mechanisms Driving Increased Thrombosis and Bleeding in Liver Disease
Increased Thrombosis 
Increased Platelet-Vesset Wall Interaction 
 •
Plasminogen • Incr PAI ... Bleeding #Clot #Cirrhosis ... Pathophysiology #Hepatology
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Management of Cirrhosis ... Indications #Management #Cirrhosis ... #treatment #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... months without treatment ... Liver #Failure #Cirrhosis ... #Hepatology #gastroenterology
Treatment of Latent Tuberculosis Infection
 - 3 mos isoniazid plus rifapentine given once weekly (Preferred)
 -
Treatment of Latent ... #Tuberculosis #treatment ... #management #infectiousdiseases ... #regimens #comparison
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
distinction has HUGE treatment ... and first-line treatment ... thrombocytopenia #Comparison ... Diagnosis #Table #Hematology
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Spherocytes • Treatment ... transient hemolysis • Treatment ... Hemolytic #Anemia #hematology ... #diagnosis #comparison
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
Gl History - Cirrhosis ... endoscopist (GEV or PHG ... Calling #Referral #Hepatology