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hematology differential treatment causes classification mds aecopd approach blood chestpain chronic cll copd disorders exacerbation hodgkins leukemia lymphocytic lymphoma macrocytic
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... transformation to acute ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... #Anemia #oncology ... #hematology #diagnosis ... #management
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... Loss • Acute ... Deficiency • Aplastic ... #Algorithm #Causes
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... progress to MDS or acute ... #Anemia #diagnosis ... #management #treatment
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... Algorithm Decreased ... • Marrow Aplasia ... Normal RBCs • Acute ... #Algorithm #Causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Aplastic Anemia ... Workup: • Complete ... #Syndromes #diagnosis ... #hematology #oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Algorithm Acute ... Disorders - Myelodysplastic ... Pelger-Huet, Macrocytic anemia ... bcr-able (+) ↑ WBC ... #Algorithm
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... High in acute blood ... #Algorithm #Diagnosis ... #Workup #Hematology
Algorithm for Management of Acute Exacerbation of COPD (AECOPD) Obtain workup for alternate diagnoses and relevant comorbidities:
Algorithm for Management ... of Acute Exacerbation ... AECOPD) Obtain workup ... for alternate diagnoses ... comorbidities: • CBC
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... Pure red cell aplasia ... ’s lymphoma or acute ... #workup #oncology
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