21 results
hematology differential management causes headache leukemia liver mds myelodysplastic neurology pathophysiology treatment abnormal apml approach arteritis cancer chronic classification cll
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... • Improve the symptoms ... #Anemia #oncology ... #hematology #diagnosis
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... and symptoms: ... progress to MDS or acute ... #Anemia #diagnosis
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... Algorithm Blood ... Loss • Acute ... Deficiency • Aplastic ... #Algorithm #Causes
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... Algorithm Decreased ... • Marrow Aplasia ... Normal RBCs • Acute ... #Algorithm #Causes
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... cytopenias (usually anemia ... transformation to acute ... treatment #hematology #oncology
Clinical manifestations of acute liver failure Brain: Hepatic encephalopathy, Cerebral edema, Intracranial hypertension,
manifestations of acute ... lung injury, Acute ... suppression, Anemia ... liver #failure #Signs ... #Symptoms #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Rare: DAH, acute ... : >3 symptoms, or ... Differentiation #Syndrome ... management #hematology #oncology
Signs and Symptoms Associated With Different Headache Etiologies • Nonfocal mental status changes - Meningitis, encephalitis,
Signs and Symptoms ... , anemia, febrile ... #headache #signs ... #symptoms #clues ... #differential #diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... - ACS, AKI, acute ... >100k, + lab signs ... #TLS #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... • Neutropenia, anemia ... ’s lymphoma or acute ... #workup #oncology
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