41 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic ... old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute ... #hematology #oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Infectious: • Acute ... • Rheumatic disorders ... effect following treatment ... Iron deficiency anemia ... #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm Acute ... - Myelodysplastic ... Pelger-Huet, Macrocytic anemia ... bcr-able (+) ↑ WBC ... #hematology #Markers
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis): • Acute ... malignancies • Anemia ... Chronic inflammatory disorders ... vera (PV) • Myelodysplastic ... #hematology #secondary
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Blood Loss • Acute ... Membrane Disorder ... Disorder - Acquired ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Neutrophils - Low RBC ... • Small Bowel Disorder ... Dysplastic • Myelodysplastic ... #Hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... Liver diseases, Myelodysplastic ... Malignant tumors, Acute ... coagulopathy (DIC) #RBC ... #differential #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Normal RBCs • Acute ... Spherocytes, RBC ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... changes), high MCV anemia ... or if a primary hematologic ... disorder is suspected ... #Workup #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... caused by blood ... Neutropenia • Platelet Disorders ... Syndromes #diagnosis #hematology ... #oncology