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diagnosis differential treatment rheumatology symptoms causes syndrome algorithm hepatology arthritis leukemia workup approach atlas classification crisis dermatology gastroenterology hepatitis infection
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... Burr Cell RBC (Echinocyte ... Bite Cell RBC: G6PD ... Target Cell RBC ... differential #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CLL Acute leukemias ... extramedullary disease ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... Infectious: • Acute ... or Chronic Inflammatory ... disorders • Celiac disease ... Iron deficiency anemia
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Diagnosis Algorithm Acute ... - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... • Lymphoid (CLL ... Blood #Disorders #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... cells can indicate disease ... • Neutropenia, anemia ... ’s lymphoma or acute ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Blood Loss • Acute ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Disease • Marrow ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... cells - Sickle cell ... Malignant tumors, Acute ... #differential #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
deficiencies: Chronic ... kidney disease, ... Index > 3: • Acute ... defects (e.g. sickle cell ... Production #Index #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
breast CA, small cell ... , Sickle cell, GVHD ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... diagnosis #algorithm #hepatology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) ... chemotherapy for low-risk disease ... #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
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