28 results
diagnosis management differential algorithm syndrome rheumatology aplastic chronic cll disorders lymphocytic lymphoproliferative mds myelodysplastic pathophysiology acidosis apml approach arteritis arthritis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... Chronic Myelogenous Leukemia ... Infectious: • Acute ... effect following treatment ... Iron deficiency anemia
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Fatigue • Acute ... (Pancytopenia, WBC ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... progress to MDS or acute ... leukemia • Associated ... #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
old, ~10,000 new cases ... cytopenias (usually anemia ... transformation to acute ... leukemia Management ... #hematology #oncology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... Blood Loss • Acute ... #Classification ... Diagnosis #Algorithm #Causes ... #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... -> AML: Blast crises ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Most common leukemia ... Vmphocytosis on routine CBC ... of anemia or thrombocytopenia ... marrow failure with anemia ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... • Neutropenia, anemia ... ’s lymphoma or acute ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... virus (EBV) • Leukemia ... Treatment: ... • Improve the symptoms ... #oncology #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
count cause hyperviscosity ... Dehydration • Symptoms ... - ACS, AKI, acute ... >100k, + lab signs ... diagnosis #management #hematology
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