14 results
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... • Neutropenia, anemia ... #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
count ↑ PLT • ↑ PBS ... develop leukostasis syndrome ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Hematology #Oncology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... progress to MDS or acute ... leukemia • Associated ... management #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... transformation to acute ... leukemia Management ... Management #treatment #hematology ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
virus (EBV) • Leukemia ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... • Improve the symptoms ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Most common leukemia ... Vmphocytosis on routine CBC ... of anemia or thrombocytopenia ... marrow failure with anemia ... #oncology #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... Episcleritis Signs ... and Symptoms: ... - CBC may also ... #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... - ACS, AKI, acute ... >100k, + lab signs ... diagnosis #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Diagnosis: >3 symptoms ... Differentiation #Syndrome ... diagnosis #management #hematology ... #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... Workup: • Complete ... #diagnosis #hematology ... #oncology