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diagnosis management hepatology algorithm differential laboratory leukemia mds myelodysplastic rheumatology aplastic apml arthritis biliary cholangitis chronic cirrhosis classification cll dermatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
marrow) -dys- (abnormal ... cytopenias (usually anemia ... transformation to acute ... Management #treatment #hematology ... #oncology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Normal range 11.5% ... High in acute blood ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Signs and Symptoms ... Proximal limb muscle wasting ... • ALT & AST normal ... cholangitis #diagnosis #workup ... #hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... (MDS) (normal or ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... #oncology #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... 500 mg QD until normal ... Differentiation #Syndrome ... diagnosis #management #hematology ... #oncology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
—100-fold with acute ... deficiency - Anemia ... leads to chronic anemia ... the hepatorenal syndrome ... Laboratory #Diagnosis #Testing
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... Treatment: Goals: Treating ... #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... ’s lymphoma or acute ... Leukemia #diagnosis #workup ... #oncology #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Acute febrile ... Episcleritis Signs ... , breast CA - Hematologic ... - CBC may also ... #oncology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
clinical symptoms/signs ... presence of metabolic syndrome ... decision for repeat testing ... body mass index; FBC ... #Algorithm #Hepatology
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