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diagnosis management aplastic chronic cll differential lymphocytic mds myelodysplastic syndrome algorithm arthritis causes cell classification dermatology disease globulin hemeonc hodgkins
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Artifact (redo CBC ... Chronic Myelogenous Leukemia ... Infectious: • Acute ... effect following treatment ... Iron deficiency anemia
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... Treatment: • Consider ... progress to MDS or acute ... leukemia • Associated ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... ’s lymphoma or acute ... #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... transformation to acute ... leukemia Management ... only curative treatment ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... activity • ↓ LAP ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Most common leukemia ... Vmphocytosis on routine CBC ... 5) Symptoms of anemia ... marrow failure with anemia ... #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
virus (EBV) • Leukemia ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... Treatment: ... #oncology #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome Acute ... Episcleritis Signs ... - CBC may also ... Treatment: - Systemic ... #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... • Plasma cell leukemia ... : Lymphoma, Leukemia ... Thalassemia, Sickle cell anemia ... inflammation (acute
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... • Hairy Cell Leukemia ... Workup: • Complete ... Syndromes #diagnosis #hematology ... #oncology
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