15 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... Renal Failure Treatment ... #diagnosis #management ... #hematology #oncology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Differential Diagnosis Algorithm ... Artifact (redo CBC ... Infectious: • Acute ... effect following treatment ... Iron deficiency anemia
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... smear: Blasts APML ... Leukemia #Hematology #Oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Acute • Myloid ... (AML) - CD13, CD33 ... T-cell - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... bcr-able (+) ↑ WBC
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... hematology for workup ... hemolysis, deficiency anemia ... Rebound effect from treatment ... • Infections: Chronic
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute ... #oncology #hematology
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Presentation ​- Acute ... anorexia, ARDS ​• RBC ... severe hemolytic anemia ... TREATMENT: ​• Acute ... Fever #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... 5) Symptoms of anemia ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology ... hemeonc #diagnosis #management
Algorithm for Management of Acute Exacerbation of COPD (AECOPD)

Obtain workup for alternate diagnoses and relevant comorbidities:
Algorithm for Management ... of Acute Exacerbation ... AECOPD) Obtain workup ... comorbidities: • CBC ... #treatment #pulmonary
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Diagnosis and Management ... incidentally via CBC ... present, symptoms, signs ... transformation into AML ... • Treatment algorithms