23 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Imaging: CXR- pulmonary ... initiation • Differential ... fluid overload, PCC ... #management #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... Drug-associated, PCH ... , Evans Syndrome ... #Diagnosis #hematology
Pulmonary Complications Following Stem Cell Transplant

For patients in the pre- engraftment period (day 0-30):
 - 
Pulmonary
- Engraftment syndrome ... Idiopathic pneumonia syndrome ... mycobacteria, and fungal- PCP ... tissue disorders #Diagnosis ... #Differential #
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... Signs and Symptoms ... Diagnosis: • ... bile ducts Differential ... #workup #hepatology
Etiologies of pulmonary infections according to CT-scan patterns. 
CMV cytomegalovirus, GM galactomannan, HSV herpes simplex virus,
Etiologies of pulmonary ... myelodysplastic syndrome ... immunofluorescence, PCR ... ComputedTomography #Differential ... #Diagnosis #Chest
Cytomegalovirus (CMV) in HIV-AIDS Patients
Cytomegalovirus (CMV): double-stranded DNA virus, herpesvirus family.
CMV infection: virus isolation or detection
of symptoms or signs ... PCR and CMV pp65 ... Pancreatitis • Pulmonary ... #differential # ... signs #symptoms
Wheezing - Differential Diagnosis Framework - Not all that wheezes is asthma
Vibrations of turbulent flow against
Wheezing - Differential ... Diagnosis Framework ... Bronchiectasis (CF-related, PCD ... plug, Carcinoid syndrome ... #pulmonary #wheeze
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Chest Pain Diagnosis and Management Algorithm
STEMI:
 - Hx: Pressure like CP, Radiation to arm/jaw, CAD risk
Chest Pain Diagnosis ... and Management ... Limb ischemia Pulmonary ... COPD, asthma, CF, PCP ... #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Donath-Landsteiner Antibodies[PCH ... Cold Agglutinin Syndrome ... younger pts) Differential ... Hemoglobinuria (PCH ... hemolytic #anemia #hematology