11 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
- Drug-induced SLE ... biliary cirrhosis (PBC ... syndrome Anti-Scl ... #diagnosis #table ... #rheumatology #
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Tuberculosis Diagnosis ... staining, NAA (PCR ... Tuberculosis #TB #Diagnosis ... #Management #Treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... : Chronic disease ... #comparison #table ... #rheumatology # ... diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Antiribosomal P, APLA, PAC ... vein thrombosis Hematologic ... La, anti-Jo-1, SCL ... Erythematosus #Diagnosis
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Tuberculosis Diagnosis ... staining, NAA (PCR ... Tuberculosis #TB #Diagnosis ... #Management #Treatment
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
and Management ... Lung Abscess Pathophysiology ... Lung Abscess Management ... Clindamycin in case of PCN ... Lung #Abscess #pulmonary
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Imaging: CXR- pulmonary ... opacities • Diagnosis ... fluid overload, PCC ... #management #hematology
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
murmur 3/6) - Pulmonary ... Recent PCI/stenting ... since elective PCI ... medical and surgical management ... stratification #diagnosis
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... : • 10%-15% Pulmonary ... Nephrogenic DI Hematologic ... muscarinic agonists • Active ... #Diagnosis #Management
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Antibiotics (Bactrim, PCN ... reabsorption) Workup ... and Elimination (see ... Table below)