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rheumatology syndrome sle comparison differential disease erythematosus hemophagocytic hlh lymphohistiocytosis systemic activetb cardiology druginduced hemeonc latenttb pharmacology summary tb tuberculosis
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... Erythematosus #Diagnosis ... #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... permeability Diagnosis ... Puncture, EEG Treatment ... #cerebritis #diagnosis ... #management #treatment
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... sle #comparison #table ... #rheumatology # ... diagnosis #management
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
sequestration and activation ... , and CXR with pulmonary ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis ... #Management #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... IFN-y) → Excessive activation ... accumulation of clinical ... Assessment • Clinical ... #management #treatment
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... La, anti-Jo-1, SCL ... Chronic B-cell activation ... Erythematosus #Diagnosis
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
and Management ... Lung Abscess - Clinical ... Clindamycin in case of PCN ... Lung #Abscess #pulmonary ... #treatment #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... excessive macrophage activation ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
antibodies (aPL): • Lupus ... at least: • 1 clinical ... presence of 1 clinical ... to be present Treatment ... #management #anticoagulation
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