14 results
Algorithm for the Evaluation and Management of Transfusion Reactions

This algorithm was developed by Dr. Eric Madden,
of Transfusion ... Reactions This ... #Transfusion #Reactions ... #Algorithm #Diagnosis ... #Management #Hematology
Transfusion Reactions - Summary Cheatsheet
 • Hemolytic Reaction
 • Febrile Reactions
 • Transfusion Related Acute Lung
Transfusion Reactions ... Cheatsheet • Hemolytic Reaction ... • Febrile Reactions ... #Reactions #diagnosis ... #management #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Reactions TRALI ... without other cause ... #Reactions #hematology ... #diagnosis #comparison ... #table
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Causes purpura & ... TRALI): Leading cause ... more likely to cause ... #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... more likely to cause ... #diagnosis #management ... #hematology #reactions
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... prosthetic valve • Transfusion ... reactions ex. ... #Differential #Diagnosis ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... reaction, Paroxysmal ... Extravascular #Causes ... #hematology #anemia
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... AIHA, Cold AIHA, Transfusion ... reactions, Drug-associated ... , PCH, Evans Syndrome ... #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Criteria for Diagnosis ... Exanthematous Pustulosis Management ... DRESS #Syndrome #dermatology ... #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
incompatible blood transfusion ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology