19 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... Smith, Sm/RNP, Scl ... #Antinuclear #Antibody ... #differential # ... diagnosis #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody ... Smith, Sm/RNP, Scl ... #Antinuclear #Antibody ... #differential # ... diagnosis #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint Pain ... Antiphospholipid-antibody ... #joint #pain #skin ... #rashes #differential ... #diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
or Anti-NucIear Antibody ... assay (IFA) is the main ... : The ANA patterns ... #rheumatology # ... diagnosis #differential
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
XR, MRI to ... difficult to see on XR ... • Differentiate ... SickleCell #Disease #differential ... diagnosis #causes #hematology
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody ... Testing Cytoplasmic Patterns ... #Antinuclear #Antibody ... #differential # ... diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... • Is there a pattern ... an asymmetric pattern ... #Differential # ... Diagnosis #MSK #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
symptoms - Pel-Ebstein ... Alcohol-induced pain ... : Pain in involved ... involvement Differential ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
effusions, weight gain ... common • Imaging: CXR ... initiation • Differential ... fluid overload, PCC ... diagnosis #management #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... - Antinuclear antibody ... titer, ACE level, CXR ... , and low back pain ... diagnosis #testing #Rheumatology