9 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
#hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications ... #druginduced
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
the Nephron #DrugInduced ... AcuteKidneyInjury #AKI #Nephrology ... #Pathophysiology ... #Pharmacology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Normotensive: • UCl ... #Hypokalemia #Differential ... Diagnosis #Algorithm #nephrology ... #causes #low #potassium
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Kat_Watson #DrugInduced ... Medication #Causes #Differential ... #Pharmacology # ... Pathophysiology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
the basis of the potassium-to-creatinine ... • Low Urine Cl ... hypokalemia #urine #potassium ... #differential # ... algorithm #diagnosis #nephrology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... • Inhibit Na+ Cl ... Piretanide Potassium ... #Diuretics #Pharmacology ... #nephrology #conversion
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Chloride Algorithm Cl ... Kidney loss of Cl ... of sodium and potassium ... urine #Algorithm #nephrology ... #differential #
Pragmatic diagnostic algorithm for hypokalemia. 
***Typical presentations: 
 • Vomiting: urine Na/Cl > 1.6, low urine
1.6, low urine Cl ... 0.7, high urine Cl ... correcting serum potassium ... hypokalemia #diagnosis #differential ... #algorithm #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Hypokalemia (renal potassium ... ratio 0.5%) Differential ... Supplement: • Potassium ... Syndrome #diagnosis #nephrology ... #management #pathophysiology