35 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
Potassium #Binding #KBinders ... Kayexelate #Comparison #Table ... #Pharmacology # ... Patiromer #HyperKalemia ... #Nephrology #Agents
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Low intake • Metabolic ... Renal Losses: • Metabolic ... Diagnosis #Algorithm #causes ... potassium #low #nephrology
Phosphate Binders - Pros and Cons

Calcium carbonate (TumsTM) 
 - Most inexpensive, antacid properties useful for
see above), no metabolic ... edgarvlermamd - Nephrology ... #Table #Comparison ... #Pharmacology # ... Nephrology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
calcium for K; also binds ... nonspecifically binds ... #medications #pharmacology ... #table #comparison ... #binders
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
Phosphate binders ... since they are not able ... restricted due to hypercalcemia ... Only* #CKD #Nephrology ... #Dose #Dosing #Pharmacology
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... Management of Hyperkalemia ... #treatment #pharmacology ... #table #comparison ... #nephrology
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... • Tumor lysis syndrome ... • Metabolic acidosis ... blockers - MCW Nephrology ... MCW_Nephrology #HyperKalemia
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... , Gitelman Syndrome ... aldosteronism #Metabolic ... Diagnosis #Algorithm #Nephrology ... #Causes
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Normotensive: • UCl ... #Hypokalemia # ... Diagnosis #Algorithm #nephrology ... #causes #low #potassium
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
wasting from other causes ... suggests extra-renal causes ... Pressure: - Metabolic ... Hippurate - Metabolic ... differential #potassium #nephrology