14 results
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Henle's loop (TAL) - Active ... tubule (DCT) - Active ... Segments #Function #Pathophysiology ... #Tubules #Table ... #Pharmacology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
syndrome - Na-K-2Cl ... Pseudohypoaldosteronism - Decreased activity ... (V2) receptor activity ... Nephrology #Diagnosis #Differential ... #Table
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
• Exogenous (KCL ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #
ANTIBIOTICS WITH ANAEROBE COVERAGE - Antibiotics Class Overview
 1. Metronidazole (Flagyl)(PO and IV)
 2. Clindamycin –
Antibiotics Class Overview ... as it also has activity ... Combined PCN/Beta-Lactamase ... #Pharmacology #Antibiotics ... #Review #Overview
Lactic Acidosis - Overview and Pathophysiology
Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
Lactic Acidosis - Overview ... and Pathophysiology ... with exercise/activity ... Acidosis #types #differential ... #diagnosis #pathophysiology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... tuberculosis (LTBI) Pathophysiology ... Risk Factors For Active ... Active: Symptomatic ... staining, NAA (PCR
Clindamycin - Antibiotics Class Overview
-50 S inhibitor (PO and IV)
Spectrum: Excellent activity vs. Anaerobes and Gram
Antibiotics Class Overview ... Spectrum: Excellent activity ... Also has activity ... vs PCP (combine ... pyrimethamine) #Pharmacology
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Overview ... tuberculosis (LTBI) Pathophysiology ... Risk Factors For Active ... Active: Symptomatic ... staining, NAA (PCR
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Antibiotics Class Overview ... other agents are: activity ... purposes including PCP ... #Pharmacology #Antibiotics ... #Review #Overview
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... Clindamycin in case of PCN ... shows a small, stable ... Lung Abscess Differential ... Abscess #pulmonary #differential