30 results
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Von Willebrand Disease ... bruising • Skin ... GI. uterine) Laboratory ... VonWillebrand #Disease ... #Diagnosis #Hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Drug-associated, PCH ... Hypophostphatemia Laboratory ... Tests: - Haptoglobin ... #hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
inhibitor • Liver disease ... • Underfilled test ... Thromboplastin #laboratory ... #hematology #diagnosis
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Generalized Differential Diagnosis ... Liver Function Tests ... Cholestatic liver disease ... #generalized #dermatology ... #Differential #Diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
pathognomonic laboratory ... tests in Behcet ... (this is a skin ... prick test that ... signs #symptoms #rheumatology
Allopecia - Differential Diagnosis Framework for Hair Loss

Localized / Focal Hair Loss Pattern:
 • Scarring Alopecia:
- Differential Diagnosis ... Capitis - Skin ... Disease: Discoid ... • Pull test ... #dermatology #Hairloss
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Diagnostic Criteria ... inflammatory disease ... Abnormal laboratory ... count >10 x 10^3/pL ... #Hematology #Dermatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
should be obtained ... more time for the laboratory ... (to support a diagnosis ... Rheumatoid #Arthritis #laboratory ... #workup #diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Hemoglobinuria (PCH ... Test: Donath-Landsteiner ... test #cold # ... hemolytic #anemia #hematology ... #diagnosis
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
• A clinical diagnosis ... other etiology • Laboratory ... blockers had the best ... disease. ... #Dermatology