21 results
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... Disorientation, vertigo Diagnostic ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Malabsorption (e.g. celiac disease ... Advanced Liver Disease ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... K), H. pylori test ... thyroid function test ... (CVID, WAS), (neurologic ... #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Elevated Liver tests ... schistocytes, DIC ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... MAHA: TTP, HUS, DIC ... Drug-associated, PCH ... Laboratory Tests ... #hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
FLAGS - In all cases ... and these should ... splenomegaly, abnormal neurology ... Rheumatology ... Peds #Pediatrics #Diagnosis
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Elevated Liver tests ... schistocytes, DIC ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... common sites: hip, shoulder ... • XR, MRI to dx ... #differential #diagnosis ... #causes #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Evolution: Chronic disease ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
screening for disease ... with established disease ... normal in mild cases ... levels (VIII, IX ... Management #treatment #hematology