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management dermatology lupus syndrome sle systemic arthritis dermatomyositis disease rheumatoid workup activation acute ana antimda5 antimda5dm antinuclear antinxp2 antinxp2dm autoantibodies
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Initial screening test ... severe disease Treatment ... diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... and Management Summary ... life-threatening • Treatment ... #Summary #rheumatology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
and Management Summary ... Diagnostic Criteria ... aspirin • Aspirin should ... #Management #Summary ... #treatment #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Systemic lupus erythematosus ... should be obtained ... (to support a diagnosis ... #testing #Rheumatology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Rheumatoid Arthritis Summary ... hands/feet, knees, shoulders ... : CLINICAL DIAGNOSIS ... exam and imaging Treatment ... #management #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
with edema • Erythematous ... , and back and shoulders ... -74%] • Blood tests ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
Diagnostic Criteria ... onset of tender erythematous ... Excellent response to treatment ... count >10 x 10^3/pL ... #Hematology #Dermatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
clinically suspected, tests ... Systemic #lupus #erythematosus ... #diagnosis #rheumatology ... #table #ANA
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... adults in the west ... phenomenon CLL Diagnosis ... microglobulin Treatment ... workup #oncology #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Liver function tests ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
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