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differential associations autoantibodies chronic cll differentiation emergencies hemeonc hodgkins leukemia lymphocytic lymphoma management mds monoclonal myelodysplasia myelodysplastic nonhodgkins oncologic paraproteinemias
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... , others (RNP, aPL ... Anti-cardiolipin (aCl ... Anti-centromere, Scl ... Autoantibodies #Rheumatology
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
Disorientation, vertigo Diagnostic ... test, TempTest ... doi: 10.1111/all ... #diagnosis #rheumatology ... #comparison #table
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... Incidence: common in APL ... fluid overload, PCC ... Differentiation #Syndrome #APML ... #hematology #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... symptoms - Pel-Ebstein ... Differential Diagnosis ... #oncology #diagnosis ... #differential #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Evans • ITP • Cl-NH ... anemia due to cold ... Paraproteinemias #Hematology ... #Differential #Diagnosis ... #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... phenomenon CLL Diagnosis ... Transform to DLBCL, PML ... #workup #oncology ... #hematology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... replacement Cord ... : - Seen with AML ... (~20 %) and APL ... #HemeOnc #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Pinpoint-sized red spots ... transformation to AML ... progression to AML ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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