17 results
Acid Base Compensation - Directions - If all three variables (pH, HCO2, pCO2) move in the
Acid Base Compensation ... variables (pH, HCO2 ... , pCO2) move in ... Diagnosis #Nephro #AcidBase
Acid-Base Disorders - Differential Diagnosis Algorithm
Acidemia (pH < 7.35)
 • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
Acid-Base Disorders ... HCO3 < 24mmol/L) CO2 ... Respiratory Acidosis (pCO2 ... Respiratory Alkalosis (pCO2 ... < 35 mmHg) #AcidBase
PLACO Mnemonic - Approach to Acid-Base Disorders
P - Determine the pH
L - Labs: PCO2 & HCO3
A
- Approach to Acid-Base ... pH L - Labs: PCO2 ... jadav_md #PLACO #AcidBase ... #Acid #Base #diagnosis
Acid Base and Blood Gas Analysis
1. pH - What’s the primary disturbance?
2. pCO2 - What’s the
Acid Base and Blood ... 2. pCO2 - What’s ... the pCO2? ... Medications, Central, ↑ CO2 ... MD @nickmmark #acidbase
Oxygen-Hemoglobin Dissociation Curve

Left Shift (↓ O2 unloading to tissue), Left = Lower:
 • ↓ H+ (↑
+ (↑ pH) • ↓ PCO2 ... tissue): • ↑ H+ (Acid ... ) • ↑ PCO2 • ... Dissociation #Curve #pathophysiology
Blood Gas (ABG) Interpretation and Acid-Base Pathology
1- Does the patient have an acidosis or an alkalosis?
Interpretation and Acid-Base ... Look at the pCO2 ... Metabolic Equal (If pCO2 ... the change in pCO2 ... MSc @AmyChung #AcidBase
Role of Uric Acid in the Inflammation of Gout

Allopurinol, Febuxostat - Xanthine oxidase
Colchicine - Release of
Role of Uric Acid ... Inflammation of Gout ... inflammation #gout ... #uricacid #pathophysiology
Acid-Base Disorders - Expected Compensation Equations

Metabolic Acidosis:
 • pCO2 = 1.5 x HCO3 + 8 ±
Acid-Base Disorders ... Acidosis: • pCO2 ... ∆ HCO3 ↓ 1 → ∆ pCO2 ... ∆ HCO3 ↓ 4 #Acid ... #Base #AcidBase
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
to filter uric acid ... like lactic acid ... and keto-acids) ... Hyperuricemia #Pathophysiology ... Complications #Gout
Gout: Pathogenesis and Clinical Findings
 - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders
 -
Gout: Pathogenesis ... -> Incr uric acid ... Chronic tophaceous gout ... Hyperuricemia #Pathophysiology ... Complications #Gout