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diagnosis hematology differential aafp anemias disorders folate folicacid homocysteine macrocytic macrocytosis mds mma myelodysplasia myelodysplastic oncology pancytopenia platelet platelets syndromes
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Differential Diagnosis Algorithm ... Reticulocytes • Abnormal peripheral ... smear Immune-mediated ... Matthew Ho, MD PhD
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Hereditary: • Peripheral ... blood smear + DAT ... #causes
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
12-13 g/dL, • ANC ... BMP, uric acid, peripheral ... smear, reticulocyte ... ↑ Destruction (hemolysis ... Matthew Ho, MD PhD
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... by ordering a peripheral ... smear, a reticulocyte ... serum level for all ... Hemorrhage or hemolysis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... plateletcount), peripheral ... blood smear, HIV ... changes), high MCV anemia ... dysplasia on the smear
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Peripheral Smear ... hematology for workup ... blood loss, Acute hemolysis ... , deficiency anemia ... Matthew Ho, MD PhD
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
result in severe anemia ... the range of Peripheral ... blood smear - Shows ... anemia Indirect ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... Smear: • Dysplastic ... Workup: • Complete ... blood smear •
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