14 results
diagnosis hematology differential blood causes clinical hemolysis aafp analysis anemias atypical auer auerrods bloodsmear disorders folate folicacid homocysteine hus interpretation
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Reticulocytes • Abnormal peripheral ... smear Immune-mediated ... Anemias (AHAs) ... Matthew Ho, MD PhD
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
Anemia Intravascular ... bilirubin LDH Peripheral ... smear Haptoglobin ... #Anemia #Laboratory ... #Testing #workup
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Smear Analysis ... DIC, TTP, HUS) ... #Blood #Smear # ... Analysis #hematology #microscopy
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Hereditary: • Peripheral ... blood smear + DAT ... anemia (TTP, HUS
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... (black arrow) Peripheral ... smear changes are ... #Pathology #Smear ... #Microscopy
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
12-13 g/dL, • ANC ... BMP, uric acid, peripheral ... smear, reticulocyte ... ↑ Destruction (hemolysis ... Matthew Ho, MD PhD
Atypical HUS - Hemolytic Uremic Syndrome Unlike typical HUS, which is shigatoxin mediated, aHUS is not typically
Atypical HUS - Hemolytic ... still present with anemia ... schistocytes on peripheral ... smear, and obtain ... #aHUS #Hemolytic
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... by ordering a peripheral ... smear, a reticulocyte ... serum level for all ... Hemorrhage or hemolysis
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... treatment, her peripheral ... blood smear showed ... BloodSmear #Blood #Smear ... #Microscopy #Auer
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 Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... - MAHA: TTP, HUS ... Defects: Sickle cell anemia ... Dehydrogenase ↑ - Peripheral ... Blood Smear ↑ abnormal
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