14 results
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
bilirubin LDH Peripheral ... smear Haptoglobin ... Laboratory #Testing #workup ... #diagnosis #hematology ... #hemolysis
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Differential Diagnosis Algorithm ... Reticulocytes • Abnormal peripheral ... smear Immune-mediated ... Matthew Ho, MD PhD ... #hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... Smear Analysis ... #Blood #Smear # ... Analysis #hematology ... #microscopy #interpretation
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
12-13 g/dL, • ANC ... BMP, uric acid, peripheral ... smear, reticulocyte ... ↑ Destruction (hemolysis ... #hematology #workup
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... smear changes are ... #anemia #Hematology ... #Pathology #Smear ... #Microscopy
Plasmodium Falciparum Blood Smear.
Key features suggesting Plasmodium falciparum:
- extreme parasitemia
- normocytic RBCs (vivax, ovale prefer big
Falciparum Blood Smear ... P. falciparum causes ... Rich Davis, PhD, ... #peripheral #clinical ... #microscopy #microbiology
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Differential Diagnosis Algorithm ... Hereditary: • Peripheral ... blood smear + DAT ... Differential #Diagnosis #Algorithm ... #causes
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Peripheral Smear ... for workup, including ... blood loss, Acute hemolysis ... Matthew Ho, MD PhD
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... plateletcount), peripheral ... blood smear, HIV ... dysplasia on the smear ... #Workup #hematology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
Algorithm for the ... by ordering a peripheral ... smear, a reticulocyte ... Hemorrhage or hemolysis ... #Workup #AAFP