12 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Megaloblastic Anemia ... Microangiopathic hemolytic anemia ... DIC, TTP, HUS) ... Autoimmune hemolytic anemia ... interpretation #clinical #anemia
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Signs of anemia ... Reticulocytes • Abnormal peripheral ... smear Immune-mediated ... #Hemolytic #Anemias
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
Here is another peripheral ... blood smear demonstrating ... iron deficiency anemia ... #Clinical #Path ... #BloodSmear #Anemia
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... DIC is a clinical ... Microangiopathic hemolytic anemia ... microangiopathic #hemolytic #anemia ... #Microscopy
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... Hereditary: • Peripheral ... blood smear + DAT ... → Sickle Cell anemia ... Microangiopathic hemolytic anemia
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
to evaluate for anemia ... thrombocytopenia, as well ... as a peripheral ... smear to evaluate ... microangiopathic hemolytic anemia
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
Wright-stained peripheral ... in sickle cell anemia ... found in hemolytic anemia ... . pernicious anemia ... #Clinical #Path
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
of macrocytic anemia ... by ordering a peripheral ... smear, a reticulocyte ... elevated, but anemia ... megaloblastic anemia
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... treatment, her peripheral ... blood smear showed ... #Clinical #Path ... #Microscopy #Auer
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Peripheral Smear ... hemolysis, deficiency anemia ... Matthew Ho, MD PhD ... Differential #Diagnosis #Algorithm