22 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Signs of anemia ... Reticulocytes • Abnormal peripheral ... smear Immune-mediated ... #hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Megaloblastic Anemia ... Microangiopathic hemolytic anemia ... Autoimmune hemolytic anemia ... Analysis #hematology ... #clinical #anemia
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
Here is another peripheral ... blood smear demonstrating ... iron deficiency anemia ... #Clinical #Path ... #BloodSmear #Anemia
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... Microangiopathic hemolytic anemia ... microangiopathic #hemolytic #anemia ... #Hematology #Pathology ... #Smear #Microscopy
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Testing in Hemolytic Anemia ... bilirubin LDH Peripheral ... smear Haptoglobin ... #Hemolytic #Anemia ... workup #diagnosis #hematology
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytes, anemia ... treatment, her peripheral ... blood smear showed ... #Clinical #Path ... #Microscopy #Auer
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... Hereditary: • Peripheral ... blood smear + DAT ... → Sickle Cell anemia ... Microangiopathic hemolytic anemia
Pancytopenia - Differential Diagnosis Algorithm
 • 12-13 g/dL,
 • ANC < 1800/uL,
 • platelet < 150,000/uL

Initial
12-13 g/dL, • ANC ... BMP, uric acid, peripheral ... smear, reticulocyte ... Matthew Ho, MD PhD ... #hematology #workup
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Peripheral Smear ... hemolysis, deficiency anemia ... Matthew Ho, MD PhD ... Differential #Diagnosis #Algorithm
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or ... Pruritis after hot bath ... - infiltrates (anemia ... smear: Blasts ... #Leukemia #Hematology