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diagnosis hematology clinical blood differential bloodsmear workup hemolysis oncology ahus analysis apl asplenia atypical auer auerrods bacilliformis bartonella causes centralpallor
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Signs of anemia ... Reticulocytes • Abnormal peripheral ... smear Immune-mediated ... Anemias (AIHAs)
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Megaloblastic Anemia ... anemia (e.g. ... anemia Sickled ... Analysis #hematology #microscopy ... interpretation #clinical #anemia
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
Anemia Intravascular ... Extravascular Hemolysis ... bilirubin LDH Peripheral ... smear Haptoglobin ... #Anemia #Laboratory
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... anemia. ... anemia is characterized ... #anemia #Hematology ... #Microscopy
Here is another peripheral blood smear demonstrating changes with iron deficiency anemia. Note the increased zone
Here is another peripheral ... blood smear demonstrating ... iron deficiency anemia ... #Clinical #Path ... #BloodSmear #Anemia
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Hereditary: • Peripheral ... blood smear + DAT ... → Sickle Cell anemia ... anemia (TTP, HUS
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
Spur-Cell Anemia ... smear showed numerous ... anemia that can ... Spur-cell anemia ... #smear
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
of macrocytic anemia ... by ordering a peripheral ... smear, a reticulocyte ... elevated, but anemia ... megaloblastic anemia
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
12-13 g/dL, • ANC ... BMP, uric acid, peripheral ... smear, reticulocyte ... ↑ Destruction (hemolysis ... Matthew Ho, MD PhD
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
Wright-stained peripheral ... in sickle cell anemia ... anemia. pernicious ... anemia, thalassemia ... #Clinical #Path
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