10 results
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... Jardiance) - Best risk ... mortality in high risk ... SGLT2 #Inhibitors #Pharmacology ... #Summary #DM2 #
Metformin - First Line Treatment for Diabetes Type 2
• Start with initial dose of 500 mg
form to minimize risk ... Indications #Titration #Pharmacology ... #Diabetes #DM2
Debridement and Management of Prosthetic Joint Infection (PJI)
Duration of symptoms <3 weeks OR  <30 days
Joint Infection (PJI ... whether benefit > risk ... Cortes_Penfield #PJI
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... outcomes in high risk ... effect) • May ↑ risk ... Receptor #Agonists #Pharmacology ... #Summary #DM2 #
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
4 Inhibitors - Pharmacology ... associated with t risk ... DPP4 #Inhibitors #Pharmacology ... #Summary #DM2 #
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
Preoperative Risk ... any modifiable risk ... Insulin dependent DM ... Recent PCI/stenting ... since elective PCI
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
carrying only a low risk ... GLP1 #Agonists #Pharmacology ... Dosing #Diabetes #DM2
Anticoagulant Therapy after PCI (patients with AFib)
Dual-Therapy Preferred:
 • Triple therapy = increased bleeding
Therapy after PCI ... - Bleeding risk ... reduced bleeding risk ... anticoagulation #PCI ... #pharmacology #
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
doxorubicin 150 mg/m2 ... , 350 mg/m2, and ... 550 mg/m2, respectively ... Identify high-risk ... cardiology #oncology #pharmacology
Lidocaine 5% Patch (Lidoderm) 
Medicare Covered Indications 
1. Post-herpetic neuralgia pain 
2. Diabetic peripheral neuropathy 
3.
indications: PHN pain, DM ... order to minimize risk ... Patch #Lidoderm #Pharmacology