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management diagnosis differential hematology gastroenterology causes pulmonary nephrology pharmacology hepatology criticalcare oncology cardiology neurology disease guidelines primarycare anticoagulation ibd obgyn
Idiopathic Thrombocytopenic Purpura Clinical: • Gingival • Menorrhagia • GI bleeding • Intracranial
Menorrhagia • GI bleeding ... children) • Platelets ... only for severe bleeding ... extremely low platelet
Indications for Transfusion Packed RBCs • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
hemoglobinopathy Platelets ... • < 30,000 and bleeding ... postoperative bleeding ... < 100,000 and bleeding ... Platelet transfusions
Bleeding and Bruising - Differential Diagnosis Algorithm • Vascular System Defect - Congenital vs Acquired •
Bleeding and Bruising ... Differential Diagnosis Algorithm ... vs Acquired • Platelet ... vs Acquired #Bleeding ... Differential #Diagnosis #Algorithm
Non-pregnant Vaginal Bleeding - Management Algorithm #Management #Vaginal #Bleeding #Nonpregnant #Algorithm #Treatment
Non-pregnant Vaginal Bleeding ... - Management Algorithm ... Management #Vaginal #Bleeding ... #Nonpregnant #Algorithm ... #Treatment
Thromboelastography (TEG) based therapy and Management If r time prolonged -> FFP If MA low -> plts/cryoprecipitate (if
cryoprecipitate If platelets ... < 50 - > platelet ... Thromboelastogram #Treatment
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Differential Diagnosis Algorithm ... B-symptoms, bruising/bleeding ... anemia, ↑ MCV, ↑/↓ platelets ... Differential #Diagnosis #Algorithm
Thromboelastogram Interpretation Reaction Time (R Value): - Time till initiation of fibrin clot - Treatment: FFP, protamine K
fibrin clot - Treatment ... representing thrombin-platelet ... interaction - Treatment ... : Platelets, DDAVP ... after MA/MCF - Treatment
Thromboelastography (TEG) Based Management - If R time prolonged -> FFP - If MA low
cryoprecipitate - If platelets ... < 50 -> platelet ... TEG #Management #treatment
Venous Thromboembolism Treatment Algorithm Branch points: Active bleeding? Active malignancy? Provoked? - Dr. Joseph Shatzel @Clotmaster #Management #VTE #DVT
Thromboembolism Treatment ... Algorithm Branch ... points: Active bleeding ... Management #VTE #DVT #Algorithm ... Thromboembolism #Treatment
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
common inherited bleeding ... bruising • Skin bleeding ... • Prolonged bleeding ... Laboratory • Normal platelet ... factor VIII) Treatment
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