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management chf hematology iron causes coagulation dic differentiation disseminated failure fallot heart heartfailure hemophagocytic hfref hlh intravascular lymphohistiocytosis oncology peds
Tetralogy of Fallot Summary • Anatomy • Incidence • Pathophysiology • Presentation • Common Variants •
• Incidence • Pathophysiology ... Tetralogy #Fallot #diagnosis ... #management #cardiology ... #peds #pediatrics ... #treatment
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Renal Failure Treatment ... fluid overload, PCC ... Differentiation #Syndrome #APML
Iron Deficiency in Heart Failure Pathophysiology: Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... Heart Failure Pathophysiology ... and iron release Diagnosis ... functional ID) Treatment ... #management #cardiology
Iron Deficiency in Congestive Heart Failure (CHF) Iron deficiency (ID) in heart failure is a common comorbidity
Iron Deficiency ... Exercise capacity Diagnosis ... depot iron] Treatment ... #pharmacology #pathophysiology ... #cardiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Cytopenia +++ (Plt ... Cellular immune deficiency ... Unknown cause Treatment ... #management #treatment
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... thrombopoietin deficiency ... + Bleeding Treatment ... #Coagulation #diagnosis ... #causes #treatment
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