12 results
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Chronic Disease Normal ... Renal Disease, Liver ... #MCV #Classification ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Overall Approach ... RBC Production - Normal ... #Classification ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
(Morphological Approach ... some patients) Normal ... : Alcohol use, Liver ... differential #diagnosis #causes ... #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary Cirrhosis ... intralobular bile ducts causes ... /Liver failure ... or higher • Liver ... diagnosis #workup #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... - If both are normal ... function may be abnormal ... hepatitis: < 1 • Cirrhosis ... diagnosis #algorithm #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Sarcoidosis) • Liver ... disease: Cirrhosis ... Thalassemia, Sickle cell anemia ... chain assay • An abnormal ... light chain • Normal
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Causes of Ascites ... Normal Peritoneum ... - Cirrhosis ... Nephrotic syndrome - Protein-losing ... #differential #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
antithrombin, protein ... DIC • Severe Liver ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
by liver insufficiency ... Prevalence: At cirrhosis ... limited Diet: protein ... Encephalopathy #Grading #Classification ... Management #treatment #hepatology