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diagnosis hematology microscopy algorithm atlas causes morphology workup agglutinin analysis bloodcell bloodsmear borrelia calculation classification cold disease disorders hemolysis hepatitis
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Smear Analysis ... anemia Sickled ... #hematology #microscopy ... interpretation #clinical
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... • Peripheral blood ... smear + DAT + further ... Hypochromic & microcytic RBCs ... #Anemia #Differential
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Hemoglobin Defects: Sickle ... cell anemia, Thalassemias ... - Peripheral Blood ... Smear ↑ abnormal
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... - Sickle cell anemia ... key #diagnosis #differential ... #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... disease, McLeod blood ... disease, Artifact Sickle ... #Morphology #differential ... #diagnosis #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... Microangiopathic hemolytic ... RBC defects (e.g ... . sickle cell anemia ... #anemia #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... smear - RBC agglutination ... younger pts) Differential ... sensitize red blood ... #anemia #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Autoimmune hepatitis, PBC ... stone, Malignancy, PBC ... , Sickle cell, GVHD ... intestines, white blood ... diagnosis #algorithm #hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
of Peripheral blood ... smear - Shows schistocytes ... , nucleated RBCs ... anemia Indirect ... count and differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... ), peripheral blood ... smear, HIV/HCV ... changes), high MCV anemia ... dysplasia on the smear
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