16 results
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood ... anemia Sickled ... red cells: Sickle ... #Blood #Smear # ... interpretation #clinical
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
Hemolytic Anemia ... Hereditary: • Peripheral ... blood smear + DAT ... Deficiency • Sickle ... → Sickle Cell anemia
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... non-specific red cell ... smear changes are ... #anemia #Hematology
Spur-Cell Anemia- A 31-year-old man with a history of cirrhosis, recurrent hepatic encephalopathy, and anemia presented
Spur-Cell Anemia ... confusion...A peripheral-blood ... anemia, a form ... of hemolytic anemia ... #peripheral #blood
Sickle cells
These photos show sickle cells on peripheral blood smears. In the left photo target cells
cells on peripheral ... blood smears. ... clinically and ... no significant anemia ... #Clinical #Path
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Hemoglobin Defects: Sickle ... cell anemia, Thalassemias ... Dehydrogenase ↑ - Peripheral ... Blood Smear ↑ abnormal
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
released in the peripheral ... Microangiopathic hemolytic ... defects (e.g. sickle ... cell anemia, G6PD ... Production #Index #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or ... - infiltrates (anemia ... • Peripheral smear ... more aggressive form ... #Leukemia #Hematology
Howell-Jolly Body - On these Wright-stained peripheral blood smears the small dark spheres within red cells
Wright-stained peripheral ... blood smears the ... autosplenectomy in sickle ... cell anemia. ... #Clinical #Path
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... smear - RBC agglutination ... sensitize red blood ... cells (RBCs) at ... #anemia #hematology