10 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Monoclonal Gammopathy ... Significance (MGUS) - Differential ... Significance #MGUS #Differential ... #Diagnosis #hematology ... #oncology
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm
 • Reactive (Inflammatory / Infectious)
 •
and Localized Lymphadenopathy ... - Differential ... #LAD #Differential ... Algorithm #Causes #Hematology ... #Oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Causes of Diffuse Lymphadenopathy ... Lymphocytes) - Monoclonal ... #LAD #Differential ... Algorithm #Causes #Hematology ... #Oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... hyperviscosity, lymphadenopathy ... #Gammopathy #Undetermined ... #Significance #hematology ... #diagnosis #oncology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
• Light chain (LC ... tubulopathy • Monoclonal ... gammopathy of renal ... #AKI #Cancer #Oncology ... #Differential #
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm
Cervical:
 - Anterior
     • Infection
Causes of Localized Lymphadenopathy ... - Differential ... #LAD #Differential ... Algorithm #Causes #Hematology ... #Oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Idiopathic monoclonal ... younger pts) Differential ... Diagnosis Monoclonal ... gammopathy of undetermined ... hemolytic #anemia #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
it represents a monoclonal ... Causes of Monoclonal ... endocrinopathy, monoclonal ... Gap #ProteinGap #differential ... #diagnosis #hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Organomegaly+↑RBC/plt ... Autoantibodies: • WAIHA • CAD ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... Significant ↓ PLT ... count • ↓Hg & PLT ... #Leukemia #Hematology ... #Oncology #Diagnosis