15 results
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... Disease, Sickle Cell ... #algorithm #hepatology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
sickle cell hepatic ... Supportive with treatment ... liver failure ... Liver transplant ... Hepatobiliary #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... breast CA, small cell ... , Sickle cell, GVHD ... intestines, white blood cells ... diagnosis #algorithm #hepatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
= funny-shaped cells ... transformation to acute ... Allogeneic stem cell ... only curative treatment ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Acute leukemias ... ALL (Acute Lymphoblastic ... Blasts APML (Acute ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... microglobulin Treatment ... ’s lymphoma or acute ... diagnosis #workup #oncology ... #hematology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Presence of CP or PC ... ) • Use of B-cell ... > 3 mg/dL) or acute ... liver failure ... Indications #management #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Release from blast cells ... • Induce blast cell ... fluid overload, PCC ... #oncology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... liver failure ... hepatocellular pattern of liver ... regarding need for treatment ... Diagnosis #Management #Hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... Schistocytes, helmet cells ... DIC • Severe Liver ... + Bleeding Treatment ... diagnosis #causes #treatment