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diagnosis syndrome lupus oncology neurology sle causes dermatology disease druginduced erythematosus summary systemic activation aih anemia anesthesia anesthesiology antinxp2 antinxp2dm
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Disease, PRES Pathophysiology ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... life-threatening • Treatment ... #Summary #rheumatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
♀, ↑Age, ESRD Pathophysiology ... heparin-PF4 complex → plt ... Diagnosis: • Clinical ... non-heparin A/C if clinical ... #Treatment #Hematology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Highly variable clinical ... Viral) Management ... regarding need for treatment ... AIH #Diagnosis #Management ... #Hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis Syndrome: • Pathophysiology ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Related Disease Clinical ... Glucocorticoids (0.6 mg/kg ... Disease #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Prednisone 5mg/kg ... APML #diagnosis #management ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... accumulation of clinical ... Cytopenia +++ (Plt ... Lymphohistiocytosis #diagnosis #management ... #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... comparison #table #rheumatology
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