28 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Cirrhosis (PBC) ... - Summary PBC ... 30-65 years PBC ... intralobular bile ducts causes ... #workup #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Intestine - Other causes ... - Drugs - Primary ... biliary Cholangitis (PBC ... Infiltrative diseases - PSC ... #Algorithm #hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
The 6 C’s of Primary ... asymptomatic at diagnosis ... #Primary #Sclerosing ... #management #summary ... #Hepatology
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
Rodents are the primary ... +/- diarrhea Diagnosis ... Treatment: • ... #Hantavirus #diagnosis ... #management #treatment
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
reported (eg AIH-PBC ... , AIH diagnosis ... Hepatitis (eg Viral) Management ... regarding need for treatment ... #Management #Hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... Renal Failure Treatment ... fluid overload, PCC ... #management #hematology
Massive Hemoptysis - Diagnosis and Management
 • Definitions: 
   - Hemoptysis = bleeding from
has potential to cause ... Cold Saline (50 Cc ... #Management #treatment ... #workup #pulmonary ... #criticalcare
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
: • Treat primary ... cause • Correct ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
and Management ... • Most common cause ... of PCN allergy ... Lung #Abscess #pulmonary ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Cytopenia +++ (Plt ... assessment+++ Primary ... Drugs, Unknown cause ... Treatment: • ... #management #treatment