10 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... Testing - Nuclear ... #Testing #Nuclear ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Reticular/AMA: • PBC ... , SSc, PBC/SSc OS ... , PBC/SjS OS • ... #Patterns #differential ... #diagnosis #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... smear, HIV/HCV testing ... #Diagnosis #Causes ... #Workup #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
) - Summary PBC ... intralobular bile ducts causes ... Proximal limb muscle wasting ... bile ducts Differential ... #workup #hepatology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Testing - Nuclear ... pattern: • SSc, PBC ... dots pattern: • PBC ... #Patterns #differential ... #diagnosis #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
initiation • Differential ... Diagnosis: Infection ... fluid overload, PCC ... #management #hematology ... #oncology
Acute Altered Mental Status - Rapid Response Management

1) Ask while en route: vitals, hyper/hypoactive, POC glucose,
Rapid Response Management ... hyper/hypoactive, POC ... Workup 5) Treat ... the underlying cause ... encephalopathy #differential
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... autoimmune hepatitis, PBC ... , PSC, Viral hepatitis ... Gap #ProteinGap #differential ... #diagnosis #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... lymph node biopsy (diagnostic ... Immunohistochemical studies (to differentiate ... Hodgkins #lymphoma #diagnosis ... #oncology #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology